IUS is a member of Kentuckiana Metroversity, Inc., a consortium of institutions of higher education in the Louisville metropolitan area. Subject to Metroversity rules and those of the host institution, a full-time undergraduate student may register for a maximum of two courses (maximum 8 credit hours) during the Fall / Spring semester only, at another member school.  Full time graduate students may take up to one course (maximum 4 credit hours) during the Fall / Spring semester only, at another member school.

IUS also participates in the Indiana College Network (ICN), a cooperative exchange between Indiana colleges and universities, which allows IUS students to supplement their degree program with courses not available on this campus.