In addition to holding over 500,000 physical books, the Library subscribes to dozens of full-text databases, and provides online access to more than a million e-books, nearly 200,000 online journals, a wide array of streaming audio and video resources, large collections of digital images, and a selection of print periodicals and newspapers. The Library also houses several special collections, including, the Center for Cultural Resources, the Curriculum Materials Center, the IU Southeast Archives, the archives of the IUS Oral History Project, and those of Ars Femina, and the William L. Simon Sheet Music Collection. Additionally, the Library is a selective depository of U.S. Government Publications.

Reference service is available whenever the library is open, and the library offers a rich array of Web-based, full-text information resources, including thousands of online newspapers and scholarly journals. Student- centered, active-learning, and learning outcomes-based instruction sessions in information literacy and library research skills are offered upon request throughout the year.

The Indiana University libraries are linked through IUCAT, a shared, Web-based catalog that furnishes access to more than 7,000,000 volumes in the IU library system and to library collections throughout the region. Access to these resources is also available from offices and computer labs across campus as well as from remote sites via the library's Web site.

Through interlibrary loan, students, faculty, and staff at Indiana University Southeast have easy access to the research collections on the Bloomington and Indianapolis campuses and around the nation. In addition, the library collections of colleges and universities in the Louisville metropolitan area are made available through Kentuckiana Metroversity cooperative agreements.