Curriculum
Courses
Faculty

• GRDM-G505 - Responsible Conduct of Research (1 cr.) The purpose of this course is to provide its students with a formal setting to learn about the basic rules and acceptable standards required for anyone conducting scientific research. It will help its students obtain knowledge and develop skills for dealing with potential ethical problems in the research laboratory on their own.
• GRDM-G507 Reagent Validation as a Means for Enhanced Research Reproducibility (1 cr.) This course is designed to provide training for pre-doctoral students in the area of appropriate reagent utilization by focusing on biological variables, with particular attention to murine models, and on biological and chemical resources, with particular attention to cell line authentication, plasmid verification, and antibody utilization.
• SURG-R520 Regenerative Medicine and Technologies Journal Club (2 cr.) An interdisciplinary course for medical and graduate students to discuss and present peer-reviewed research in regenerative medicine and technologies. Faculty attend at the request of the students to discuss recent research findings and topics not generally covered in traditional graduate curricula. Required for the Regenerative Medicine and Technologies master’s program. Required as part of the Regenerative Medicine and Technologies masters and doctoral majors.
• SURG-R711 Regenerative Medicine, Biomaterials, and Therapeutics (2 cr.) This sixteen-week course will cover eleven lectures by prominent experts. Students will have an overview of biomaterials and therapeutics used in Regenerative Medicine. Emphasis will be given on fundamentals and advancements made in nano-biomaterials for delivery of therapeutics in Regenerative Medicine. The curriculum will also include a paper presentation at the end. Required as part of the Regenerative Medicine and Technologies masters and doctoral majors.
• SURG-R712 Regenerative Medicine Technology Development and Manufacturing (2 cr.) This course provides students with an overview of development and manufacturing of Regenerative Medicine products. From the science behind groundbreaking discoveries to regulatory and manufacturing challenges, the curriculum will detail multi-disciplinary collaboration and technology integration with a student seminar at the end. Required as part of the Regenerative Medicine and Technologies masters and doctoral majors.
• SURG-R720 Research Rotation in Regenerative Medicine and Technologies (2 cr.) A laboratory research rotation course allowing incoming Regenerative Medicine and Technologies MS and PhD graduate students in the School of Medicine (IUSM) to take research rotations in laboratories affiliated with the RMAT graduate programs. Permission of instructor required. Required as part of the Regenerative Medicine and Technologies doctoral major. Optional for RMAT MS students.
• SURG-R719 Regenerative Medicine and Technologies Thesis (6 cr.) This is an introductory course in thesis methodology and writing. The course guides students to complete the master’s thesis, or the first three chapters of the traditional doctoral dissertation, through readings, peer review, and instructor feedback. Required as part of the Regenerative Medicine and Technologies master’s major. Prerequisites: SURG-R991, SURG-R980.
• SURG-R780 Advanced Topics in Regenerative Medicine and Technologies (3 cr.) Advanced course in regenerative medicine technologies, manufacturing regulations, and standards for healthcare applications. The curriculum will detail multi-disciplinary collaboration and technology integration.
• SURG-R791 Industry/Clinical Internship (4 cr.) An internship course allowing graduate students enrolled in programs that require internships to gain practical experience with ICRME’s industry partners. Instructor permission required.
• SURG-R800 Research in Regenerative Medicine and Technologies (variable cr.) This course is the academic component of laboratory-based research that a student in a Regenerative Medicine and Technologies program engages in while a student in the program. This course addresses both research conducted in a lab prior to the start of a thesis/dissertation project and the thesis/dissertation project itself. Instructor permission required.
• BME 52700 Implantable Systems (3 cr.) Engineering constraints surrounding the selection of a power source for an implantable system and in particular how the control of the target organ system impacts power plant design. The organ specific design of cochlear neuroprosthetics, functional neuromuscular stimulation systems and cardiac pacemakers are presented in detail as but three examples of technically mature implantable systems that have had broad clinical impact. For each, there is a brief introduction to the related anatomy, physiology and neurophysiology of the target organ system so that students may gain perspective on the functional limits of the artificial control of these organ systems. Several implantable systems presently in the early stages of bioengineering design or in the early stages of clinical trials are presented as state-of-the-art examples. Particular attention is given to practical bioengineering issues related to the ever expanding use of implantable biomedical sensors in order to provide real-time control of the implant and improved response to challenges to the homeostasis of organ system function. Issues related to ethical and regulatory considerations related to implantable system design including animal testing, human clinical trials and FDA premarket approval are also introduced.
• BME 58200 Advanced Biomedical Polymers (3 cr.) This is an advanced polymer course that provides the most recent development of biomedical polymers and their applications and covers a variety of biomedical areas such as in cardiovascular, dental, orthopedic, ophthalmologic and wound healing research. Drug, cellular and gene delivery are also covered. This course is designed for all the senior undergraduate and graduate students (M.S. and Ph.D. level) in biomedical areas. Except for learning, students are also required to discuss the related topics and write term papers related to the assigned special topics in the class.
• BME 59500 Biomolecular Engineering (3 cr.) This course covers the experimental and computational tools useful to analyze biological molecules and molecular systems, potential applications of DNA/protein molecules for designing nano-scale motors, switches, and computers. The topics include electrophoresis, genome-wide molecular analysis, network analysis, DNA manipulations, protein interactions, and microfluidics.
• BME 59500 Cellular Mechanotransduction (3 cr.) This course will cover the biochemical signaling in response to various mechanical stresses in the context of physiology and pathophysiology. Topics include the behavior of live cells during cell motility, force generation, and interaction with the extracellular matrix; the advanced biomechanical testing tools used for in vitro characterization of living cells; mechanotransduction that converts mechanical forces into biochemical signaling.
• BME 59500 Tissue Engineering (3 cr.) This course will cover biological principles and physiological phenomena underlying cellular regulation during development, homeostasis, and wound healing. Topics also include tissue engineering fundamentals, such as cell sources, transplantation immunology, processing of scaffolding materials, integration at cell-material interfaces, mechanisms of incorporation and release of biologics, engineered culture environments, and host-transplant integration. Students will have opportunity to evaluate clinically relevant tissue engineering products and cutting-edge tissue engineering research.
• SURG-R780 Advanced Topics in Regenerative Medicine and Technologies (3 cr.) This sixteen-week course will cover eleven lectures by prominent experts to provide an overview of groundbreaking discoveries, regulatory and manufacturing challenges, Emphasis will be given on advanced regenerative medicine technologies, manufacturing regulations, and standards for healthcare applications. The curriculum will detail multi-disciplinary collaboration and technology integration.
• GRDM-G661 Clinical Trials (3 cr.) This course includes topics in conducting clinical trials, including design, recruitment, informed consent, randomization, blinding, data collection and analysis, safety monitoring, study closeout, and alternative designs such as crossover and nonrandomized trials. Some important research areas besides clinical trials are also covered.
• GRAD-G715 Biomedical Science I (2 cr.) One of three biomedical science courses intended for incoming doctoral graduate students in the School of Medicine or other graduate students. The material presented addresses molecular and metabolic aspects of cellular function. The course will explore topics in the biochemical basis of biological systems, including biological macromolecules, protein ligand interactions, cell signaling, and metabolic processes.