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Clinical Laboratory Science | CLS

Moses SaidiPictured | Moses Saidi  | Bachelor of Science in Clinical Laboratory Science | MLT, Malamulo College of Health Sciences (Makwasa Malawi) | Blantyre, Malawi (hometown)
Club Affiliation | International Students Club


Clinical Laboratory Science | CLS

P Prerequisite | C Co-requisite | R Recommended
I Fall Semester | II Spring Semester | S Summer Session/s


  • CLS-B 399 Human Behavior and Social Institutions (3 cr.) This course provides an entry level understanding of the clinical laboratory management team responsibilities. Topics include general management theories, federal regulations and government organizations, financial management, operations management, human resources, and career success and development. Human behaviors and social interactions are further explored and applied in independent and group projects.
  • CLS-C 405 Clinical Chemistry (3 cr.) P: Requires meeting the application requirements for program entry. Clinical Chemistry is one of the key disciplinary areas for entry level competency as a Clinical or Medical Laboratory Scientist. This course covers the standard competencies in clinical chemistry tested in the ASCP BOC exam for generalists in Medical Laboratory Science (MLS). Students will examine the basic principles and practices used in the clinical chemistry laboratory including fundamental mathematics for laboratory measurements, analytical techniques, and clinical correlations. An emphasis will be placed on acid base balancing, lipid and protein identifications, enzymatic action, and their correlation with the endocrine system in clinical diagnostics.
  • CLS-C 406 Diagnostic Methods (2 cr.) In conjunction with CLS-C 405 Clinical Chemistry, students will be exposed to the basic and fundamental principles of contemporary medical laboratory diagnostic practice, through practical laboratories that present both the principle and procedure for basic and common diagnostic laboratory techniques conducted manually or with instrumentation.
  • CLS-C 407 Hematology (3 cr.) P: Must meet application requirements for program entry. This course is an essential component of the CLS curriculum. Hematology is one of the key disciplinary areas for entry level competency as a Clinical or Medical Laboratory Scientist. This course covers standard competencies in routine hematology tested in the ASCP BOC exam for generalists in Medical Laboratory Science (MLS). Students will examine the foundational principles of routine hematologic diagnostics including hemostasis, hemoglobin synthesis, and hematological disorders. A focus will be given in the areas of erythrocyte and leukocyte morphology and biology as well as a focus on the use of these cells in the diagnosis of disease. It should be taught in conjunction with the laboratory course CLS-C 408.
  • CLS-C 408 Hematology Methods (2 cr.) C: CLS-C 407. In conjunction with CLS-C 407 Hematology, students will be exposed to the basic and fundamental principles of contemporary medical laboratory hematology practice, through practical laboratories that present both the principle and procedure for basic and common hematological laboratory techniques including red and white cell differentiation, erythrocyte sedimentation, and traditional blood smear.
  • CLS-C 415 Clinical Molecular Diagnostics and Special Chemistry (3 cr.) P: CLS-C 405 and CLS-C 406. Clinical Molecular Diagnostics and Special Chemistry is an upper division course in the Clinical Laboratory Sciences. Entry into this course is limited to students currently coded into the clinical track for CLS. Students should have previously completed both CLS-C405 and CLS-C406. This course is focused on providing advanced practical skills in clinical chemistry and molecular diagnostic techniques utilized in the field of medical laboratory science.
  • CLS-C 417 Advanced Hematology and Cancer (3 cr.) P: CLS-C 407 and CLS-C 406; or entry into the MLT to CLS Degree Completion Program. Advanced Hematology and Cancer introduces the student to advanced topics in the development of malignancy, with an emphasis on hematological malignancies and other cancers diagnosed through blood and body fluid specimen collection techniques, as well as hematological disorders commonly found through testing in the clinical diagnostic space. Molecular, Immunological, and immunophenotyping techniques are examined in relation to widespread and well established hematological disease profiles.
  • CLS-E 401 General Externship I (2 cr.) P: Successful completion of CLS courses M403, M404, M411, M413, C405, C406, I407, I408, C407, C408, C409, and L420 The General Externship I is one of four sequential externship courses that occur during the senior year in the MLS program. General Externship I takes place during weeks 1-4 of the spring semester. During the clinical rotations, students receive hands-on experience in all commonly practiced areas in the diagnostic laboratory.
  • CLS-E 402 General Externship II (2 cr.) P: Successful completion of CLS courses M403, M404, M411, M413, C405, C406, I407, I408, C407, C408, C409, and L420. The General Externship II is one of four sequential externship courses that occur during the senior year in the MLS program. General Externship II takes place during weeks 5-8 of the spring semester. During the clinical rotations, students receive hands-on experience in all commonly practiced areas in the diagnostic laboratory.
  • CLS-E 403 General Externship II (2 cr.) P: Successful completion of CLS courses M403, M404, M411, M413, C405, C406, I407, I408, C407, C408, C409, and L420. The General Externship III is one of four sequential externship courses that occur during the senior year in the MLS program. General Externship III takes place during weeks 9-12 of the spring semester. During the clinical rotations, students receive hands-on experience in all commonly practiced areas in the diagnostic laboratory.
  • CLS-E 404 General Externship IV (2 cr.) P: Successful completion of CLS courses M403, M404, M411, M413, C405, C406, I407, I408, C407, C408, C409, and L420. The General Externship IV is one of four sequential externship courses that occur during the senior year in the MLS program. General Externship IV takes place during weeks 12-16 of the spring semester. During the clinical rotations, students receive hands-on experience in all commonly practiced areas in the diagnostic laboratory.
  • CLS-E 406 Supplemental Externship (1-2 cr.) P: students in the MLT to CLS Degree completion track. This course is available for MLT to CLS degree completions students who want to experience a clinical rotation in an area of the clinical laboratory. Students will be placed in regional laboratory and hospital organizations, within a reasonable distance, and with consideration of student living and transportation needs.
  • CLS-I 407 Immunohematology and Transfusion Medicine (3 cr.) Biomarkers can be used to minimize the risks associated with the common practice of blood transfusion and blood banking, technically defined as immunohematology. This course covers both the conventional concepts and practices of antigen/antibody utilization in the blood bank and advanced discussions of the blood bank in transfusion medicine.
  • CLS-I 408 Blood Banking Methods (2 cr.) Taught in conjunction with CLS-I 407 Serology and Immunohematology. CLS-I 408 Blood Banking Methods provides practical laboratory components useful for conducting diagnostic testing in the blood bank and immunological laboratory setting. Laboratory lessons will be on acquiring the fundamental skills in lab technique and etiquette prior to clinical Externships.
  • CLS-I 411 Clinical Innunodiagnostics (2-3 cr.) Clinical Immunodiagnostics is the study of the analysis of antibodies¬† as biomarkers in the diagnosis of disease and the use of antibodies as reagents in the detection of biomarkers of disease. This course is a requirement for the program in Clinical Laboratory Science at Indiana University South Bend.
  • CLS-I 417 Advanced Diagnostic Immunology, Transfusion and Autoimmune Disease (3 cr.) P: CLS-I 407 (or equivalent). This course is a requirement for the program in Clinical Laboratory Science provided through the Vera Z. Dwyer College of Health Sciences, built in alignment with the NAACLS accreditation agency for Medical Laboratory Science (MLS).¬† Students enrolled in this course will be taught the advanced entry level curriculum necessary for processional certification by the ASCP BOC in diagnostic immunology, transfusion and autoimmune disease.
  • CLS-L 201 Introduction to the Diagnostic Laboratory (1 cr.) P: Some basic science recommended. This course functions as a basic introduction to the field of Clinical Laboratory Sciences. Covering all of the major sub disciplines found in laboratory diagnostics; including clinical chemistry, hematology, microbiology, and others, this course is useful for students interested in pursuing a career in laboratory science or who are curious about the role of laboratory professionals in interdisciplinary healthcare.
  • CLS-L 202 Laboratory Math and Techniques (1 cr.) This course is designed as the second of two introductory courses in Clinical Laboratory Science. Students enrolled in this course will be introduced to the practical application of mathematical operations and laboratory techniques as they apply to the clinical diagnostic laboratory field.
  • CLS-L 420 Urinalysis and Body Fluid Analysis (2 cr.) This course is a requirement for the program in Clinical Laboratory Science provided through the Vera Z. Dwyer College of Health Sciences, built in alignment with the NAACLS accreditation agency for Medical Laboratory Science (MLS). Students enrolled in this course will be taught the entry level curriculum necessary for processional certification by the ASCP BOC in diagnostic urinalysis and body fluid analysis.
  • CLS-M 403 Clinical Microbiology (3 cr.) P: This course is part of a Clinical track in Clinical Laboratory Science. It will require meeting the application requirements for program entry. Clinical microbiology is one of the key disciplinary areas for entry level competency as a Clinical or Medical Laboratory Scientist. This course covers standard competencies in routine microbiology tested in the ASCP BOC exam for generalists in Medical Laboratory Science (MLS). Students will examine the foundational principles of clinical microbiology including a focus on the most common microorganisms involved in infection and there classification. Microorganisms will be defined by traditional biochemical differentiation patterns, however an additional emphasis on contemporary immunological and molecular approaches to identification will also be explored. It should be taught in conjunction with the laboratory course CLS-M 404.
  • CLS-M 404 Microbiological Methods (2 cr.) C: CLS-M 403. Should be taught in conjunction with CLS-M403 Clinical Microbiology, students will be exposed to the basic and fundamental principles of contemporary medical laboratory microbiology practice, through practical laboratories that present both the principle and procedure for basic and common chemical laboratory techniques.
  • CLS-M 411 Mycology and Parasitology (2 cr.) This course is a requirement for the program in Clinical Laboratory Science provided through the Vera Z. Dwyer College of Health Sciences, built in alignment with the NAACLS accreditation agency for Medical Laboratory Science (MLS). Students enrolled in this course will be taught the entry level curriculum necessary for processional certification by the ASCP BOC in diagnostic mycology and parasitology.
  • CLS-M 413 Advanced Clinical Microbiology (3 cr.) P:  Students should have already completed CLS-M 403 and CLS- M 404; or be alternatively be admitted the MLT to CLS degree completion program. This course is an advanced course in clinical Microbiology available to students who have been successfully admitted the clinical program in Clinical Laboratory Science. Students in this course will be introduced to advanced methods used in the microbiological laboratory including but not limited to an examination of serological and molecular approaches, vaccination from infection, and agents of bioterrorism.
  • CLS-M 450 Clinical Laboratory Management, Ethics and Policy (3 cr.) This course covers an entry level understanding of the specifics of laboratory management including policy and ethical responsibilities and authorities. Classes delve into five major areas beginning with strategies for career success, and discussing the key areas of laboratory management, human resources, financial management and operations. Students will be asked to incorporate these key managerial aspects in a lab development mock-up exercise.
  • CLS-N 390 The Natural World (3 cr.) Explores an important scientific or technological issue in modern society. Applies scientific methods and interdisciplinary perspectives in an examination of the subject. Investigates the broader implications and ethical dimensions of scientific research and technological advancement.

Academic Bulletins

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2023-2024 Campus Bulletin
2022-2023 Campus Bulletin
2021-2022 Campus Bulletin
2020-2021 Campus Bulletin
2019-2020 Campus Bulletin
2018-2019 Campus Bulletin
2017-2018 Campus Bulletin
2016-2017 Campus Bulletin
2015-2016 Campus Bulletin
2014-2015 Campus Bulletin

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