Chair: Professor Rhoades

Graduate Director: Associate Professor Pavalko

F305 Human Physiology (90 hrs.) (5 cr.) For allied health students. One-semester lecture and discussion. Human physiology covering neuromuscular, respiratory, circulatory, gastrointestinal, renal, and endocrine systems. Emphasis in discussion on application of physiological principles to professional practice. Meiss and Staff

F499 Independent Research in Medical Physiology and Biophysics (1-4 cr.) Research for undergraduate students. Introduction to research methods and scientific investigation in medical physiology and biophysics. Research areas include membrane biophysics and transport, neurobiology/ neurophysiology, respiratory physiology, muscle physiology, vascular physiology, renal physiology, and endocrinology. Staff

F513 Human Physiology (176 hrs.) (6 cr.) For School of Medicine students. Coverage in lectures and laboratories of neurophysiology, physiology of muscular activity, respiration, circulation, excretion, gastrointestinal physiology, metabolism, and acid-base balance and reproductive physiology; emphasis on basic physiological mechanism, but clinical application stressed wherever possible. Peavy and Staff

Graduate Courses and Electives

The courses listed below are primarily intended for students seeking the M.S. or Ph.D. degree in physiology, and for medical students seeking a combined M.D. and graduate degree. Complete program information is provided in the Indiana University Graduate School Bulletin and/or departmental brochures.

F503 Human Physiology (4 cr.) P: Introductory biology (K101, K103), organic chemistry (C341, C342), and physics (P201, P202); or equivalent. Advanced course in human physiology designed for students with no prior exposure to the discipline. Emphasis on basic physiological mechanisms of control with regard to membrane, neural, endocrine, reproductive, muscle, cardiovascular, respiratory, gastrointestinal, renal, and multisystems physiology. Staff

F592 Biophysics Radioisotope Methodology (45 hrs.) (3 cr.) Basic properties of radioisotopes; characteristics and utilization of instrument systems; design and analysis of experiments in physiology. Staff

F595 Advanced Physiology (cr. arr.) P: consent of instructor. Special techniques in advanced areas of physiology. Staff

F596 Physicochemical Basis of Physiology (3 cr.) P: consent of instructor. Review of selected physicochemical principles, e.g., modern thermodynamics, electrochemistry, solution theory, water structure, molecular interactions, with special emphasis on their application to physiological problems. Staff

F613 Mammalian Physiology Lecture (5 cr.) Neurophysiology, physiology of muscular activity, respiration, circulation, gastrointestinal physiology, excretion, metabolism, and endocrinology. Emphasis on basic physiological mechanisms and control. Staff

F650 Membrane Biophysics (3 cr.) Structure and function of special membranes; mitochondria, RBC, nerve and muscle. Duncan

F701 Research in Physiology (cr. arr.) Staff

F702 Seminar in Physiology (1 cr.) Staff

F705 Molecular and Cellular Physiology (3 cr.) The emphasis is on the intracellular mechanisms which underlie the physiological functions of many organ systems. Three fundamental topics will be discussed: membrane transport, physiology of excitable membranes and contraction, and endocrine regulation. Current research techniques in these areas will be discussed. Kempson

F710 Physiology of Membranes (2 cr.) P: consent of instructor. Structure and function of cell membranes. Kinetics and energetics of membrane transport. Regulation of intracellular ionic concentrations. Hormonal and pathophysiological modification of membrane function. Staff

F712 Physiology of the Circulatory System (45 hrs.) (2 cr.) Hemodynamic principles; cardiac regulation and vasomotor control; pressure pulses; cardiac output, work, and adaptation; special circulation. Bohlen

F724 Physiology of Nerve (3 cr.) P: F613. Excitation and conduction of the nerve impulse. Axoplasmic transport and nerve maintenance. Synaptic transmission and trophic control. Reflexes. Friedman

F725 Muscle Macromolecules and Contraction (2 cr.) Structure and function of various macromolecules involved in muscle contraction. The aspects covered include excitation-contraction coupling, regulation of myoplasmic free calcium level, the contractile machinery, and force generation. Comparison in skeletal, cardiac, and smooth muscles. Lectures and guided discussion of papers. Hui and Packer

F734 Blood Gases and Respiration (30 hrs.) (2 cr.) Pulmonary mechanics and gas exchange, gaseous transport and uptake by tissues, acid-base balance, central and reflex control of respiration, respiratory problems in altitude and deep-sea physiology, and modern techniques in respiratory physiology. Rhoades and Wagner

F752 Physiology of the Gastrointestinal System (30 hrs.) (2 cr.) Mechanics of digestive tract; secretory mechanism of digestive glands; digestion and absorption of the major foodstuffs. Staff

F765 Physiology of the Endocrine System (2 cr.) P: F613. Regulation of secretions of the endocrine glands, including neuroendocrine system, action of the hormones; roles of hormones in maintenance of a constant internal environment; physiology of reproduction. Peavy and Donner

F772 Physiology of Body Fluids and Electrolytes (30 hrs.) (2 cr.) Composition and distribution of body fluids and electrolytes; renal regulatory role; factors concerned with glomerular filtration rate and blood flow; tubular function; handling of organic and inorganic substances; chemistry and physics of the transfer of mechanism; role of hormones. Kempson and Tanner

F780 Special Topics in Physiology (cr. arr.) Tutorial instruction in physiology. Staff

G706 Cell-Cell Communication (4 cr.) P: consent of instructor. This course provides a basic understanding of chemical mechanisms of cellular communication, including the functional, biochemical, and molecular mechanisms of the communication processes involved. Modern techniques of signal transduction physiology will be covered through critical analysis of primary research literature. Elmendorg and Herring

G760 Epithelial Cell Biology (3 cr.) P: graduate mammalian physiology/biology or consent of instructor. An integrated approach to epithelial structure and function and the role of subcellular organization in organ physiology and pathophysiology. Kempson and Marrs

G818 Integrative Cell Biology (3 cr.) This course provides broad understanding of ways in which cells are organized and integrated into tissues. Emphasis is on the function of cells in neural/neuroendocrine system, cardiopulmonary, renal, and immune systems and in cytomechanics. Modern approaches to the study of tissue function by analysis of cellular regulations will be emphasized.

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