Recommendations
Mathematics M211 or M215 is strongly recommended, and M212 or M216 is highly desirable for students planning to work in many other fields.

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Major in Biochemistry—B.A.

Purpose
This major is designed for students planning to attend medical or dental school, but who cannot meet all requirements for the B.S. in biochemistry and who do not plan to pursue graduate work or to seek employment in industry. Students must complete the following course work with a grade of C- or better in each course:

1. C117 (or C105-C125), C118 (or C106-C126), C341, C342, C343, C484, C485, and C487.
2. A minimum of 3 credit hours selected from the following: C317, C318, C344, C360, C430, C460.
3. Biology L112.
4. Mathematics M119 or M211 or M215.
5. Physics P201 or P221.

Recommendations
Mathematics M211 or M215 is strongly recommended, and M212 or M216 is highly desirable for students planning to work in other fields.

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Major in Chemistry—B.S.

Purpose
The B.S. in chemistry is designed to prepare students for graduate work and for jobs in industry as well as for medical and dental schools.

Requirements
Students must complete the following fundamental skills and distribution requirements:

1. Writing, same as B.A. degree.
2. Foreign language, 3 credit hours of any foreign language at the second-year level.
3. Arts and humanities, two courses.
4. Social and historical studies, two courses.
5. Biology, one course.
6. Natural and mathematical sciences, fulfilled by major.

1. 45 credit hours of chemistry, including C315, C317, C318, C341, C342, C343, C344, C361, C362, C364, C430, C471, and either C483 or C484. C103, C240, and G499 may not be counted in the 45 credit hours required for the major.
2. Mathematics M211 or M215, M212 or M216, and M303, M311, or M343.
3. Physics P221-P222.

Recommendations
Mathematics M311 is recommended over Mathematics M303 or M343.

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Major in Biochemistry—B.S.

Purpose
The B.S. in biochemistry is designed for students planning to attend medical or dental school, to do graduate work in biochemistry, or to seek employment in industry.

Requirements
Students must complete all of the following fundamental skills and distribution requirements:

1. Writing, same as B.A. degree.
2. Foreign language, 3 credit hours of any foreign language at the second-year level.
3. Arts and humanities, two courses.
4. Social and historical studies, three courses.
5. Natural and mathematical sciences, fulfilled by major.

1. 45 credit hours of chemistry, including C315, C317, C318, C341, C342, C343, C344, C361-C362 or C361-C481, C364 or C487, C471, C484, C485. C103, C240, and G499 may not be counted in the 45 credit hours required for the major.
2. Mathematics M211 or M215 and M212 or M216.
3. Physics P221-P222.
4. Biology L112 and at least one of the following: L311, L312, M250-M255, M350, M430.

Recommendations
Chemistry C487 is recommended over Chemistry C364. Chemistry C481 is recommended over Chemistry C362.

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Chemistry Minor

Requirements
17 credit hours or more in chemistry.

1. Required Core Courses: Chem C117 (or C105-C125), C118 (or C106), and C341.
2. Electives: Select 2 courses from the following list of lecture courses (4-6 credit hours): C317, C318, C342, C360, C361, C362, C430, C432, C443, C460, C481, C483, C484, C485.
3. 12 credit hours of courses taken for the minor must be taken on the Bloomington campus.
4. A minor GPA of 2.0 is required with no course grade lower than C-.

Departmental Honors Program

The program is designed for especially well-qualified students who wish to acquire an unusually strong foundation in chemistry. Most students completing the honors program enter graduate or professional school. Special courses for outstanding students are offered in general chemistry, S117 (or S105-S125), S118 (or S106-S126); and in organic chemistry, S341, S342, S343, and S344. Participants are expected to complete the requirements for a B.S. in chemistry or a B.S. in biochemistry or the following courses: C315, C317, C318, C361, C362, C364, and two 3 credit hour, 400-level courses other than C409 and C445.

The heart of the honors program is participation in an undergraduate research project within a faculty research group. This research generally begins in the freshman or sophomore year and culminates with an honors research thesis at the end of the senior year. Students in the program must maintain a minimum grade point average of 3.3.

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Course Descriptions

C100 The World as Chemistry (3 cr.) N & M For non-science majors, the chemistry of everyday life: fuels, plastics, drugs, water, air, and living systems. Lectures illustrated by demonstrations, films, and molecular models. Readings include articles from current newspapers and magazines. Prerequisite: Curiosity. Credit given for only one of C100, C101, C105, S105, C117, or S117. I Sem., II Sem.
C101 Elementary Chemistry I (3 cr.) N & M Usually taken concurrently with C121. Introduction to chemistry. The two sequences, C101-C121 and C102-C122, usually satisfy programs that require only two semesters of chemistry. Admission to advanced courses on the basis of C101-C121and C102-C122 is granted only in exceptional cases. May be taken in preparation for C117 by students with deficiencies in chemistry. Credit given for only one of C100, C101, C105, S105, C117 or S117. I Sem., II Sem., SS.
C102 Elementary Chemistry II (3 cr.) N & M P: C101. Usually taken concurrently with C122. Continuation of C101. The chemistry of organic compounds and their reactions followed by an extensive introduction to biochemistry. Credit given for only one of C102, C106, S106, C118 or S118; however, for students electing to major in allied health sciences after having taken C106, S106, C118, or S118, credit may also be received for C102 with consent of the chemistry undergraduate advisor. II Sem.
C103 Introduction to Chemical Principles (5 cr.) N & M P: Scores on placement exams and instructor's permission. To be taken as preparation for C117. Content includes: applications of measurement and chemical formula/equation conversions; modern view of the atom; and solution processes that relate to chemical reactions. Emphasis of lectures and discussion sections will be problem-solving strategies.
C117 Principles of Chemistry and Biochemistry I (5 cr.) N & M P: Two years of high school algebra or Math M014; one year of high school chemistry. Introduction to the basic principles of chemistry and biochemistry with their applications to physiological (biochemical) functions. An integrated lecture-laboratory course covering basic principles of chemistry and biochemistry. First semester of a two-semester sequence. Credit given for only one of the following: C101-C121, C105-C125, S105-S125, C117 or S117. I Sem., II Sem., SS.
S117 Principles of Chemistry and Biochemistry I, Honors (5 cr.) N & M P: Placement examination or consent of department. For students with unusual aptitude or preparation. An integrated lecture-laboratory course covering basic principles of chemistry and biochemistry. First semester of a two-semester sequence. Credit given for only one of the following: C101-C121, C105-C125, S105-S125, C117 or S117. I Sem.
C118 Principles of Chemistry and Biochemistry II (5 cr.) N & M P: C117 or C105-C125. Introduction to the basic principles of chemistry and biochemistry with their applications to physiological (biochemical) functions. An integrated lecture-laboratory course covering basic principles of chemistry and biochemistry. Second semester of a two-semester sequence. Credit given for only one of the following: C102-C122, C106-C126, S106-S126, C118, or S118. I Sem., II Sem., SS.
S118 Principles of Chemistry and Biochemistry II, Honors (5 cr.) N & M P: S117 or consent of department. For students with unusual aptitude or preparation. An integrated lecture-laboratory course covering basic principles of chemistry and biochemistry. Second semester of a two-semester sequence. Credit given for only one of the following: C102-C122, C106-C126, S106-S126, C118 or S118. II Sem.
C121 Elementary Chemistry Laboratory I (2 cr.) P or C: C101. Introduction to the techniques and reasoning of experimental chemistry. Credit given for only one of the following: C117, S117, C121, C125, or S125. I Sem., II Sem., SS.
C122 Elementary Chemistry Laboratory II (2 cr.) P: C101, C121. P or C: C102. Continuation of C121. Emphasis on organic and biochemical experimental techniques. Credit given for only one of the following: C118, S118, C122, C126, or S126; however, for students electing to major in allied health sciences after having taken C118, S118, C126, S126, credit may also be received for C122 with consent of the chemistry undergraduate advisor. II Sem.
G207 Chemical Scholarship and Presentation (1 cr.) P: Sophomore standing; Chemistry or Biochemistry majors. Involves the preparation of scientific oral presentations and poster presentations. Assignments include the making of slides, using presentation software, handling of scientific data correctly, and presentation skills. Students will give presentations as the final assignment. Not repeatable for credit.
C240 Preparation for Organic Chemistry (1.5 cr.) P: C106 or C118, or permission. To develop a standard and comprehensive preparation for the study of organic chemistry. Review of electronic structure, periodicity, bonding, Lewis structures, pKa's, simple nomenclature and molecular geometry; Problem-based approach to developing skills necessary for success in organic chemistry. Course will not count toward chemistry minor or majors.
G307 Chemical Career Planning (1 cr.) P: Junior standing; Chemistry or Biochemistry major. Focuses on writing resumes, personal statements and cover letters. Content includes interviewing skills, discussion of graduate programs and careers in chemistry, personal assessment, job searching strategies, labor market trends, and principles of career planning. Not repeatable for credit.
A314 Biological and Environmental Chemical Analysis (4 cr.) P: C118. Theory and application of analytical techniques including statistical treatment of data, spectroscopy, separation methods, electroanalytical methods, radioisotopes, and immunological methods. Laboratory experiments will emphasize chemical methods used for environmental and biological analysis.
C315 Chemical Measurements Laboratory I (3 cr.) P: C317, C318. Experimental work in related areas of chemical analysis, instrumentation, and elementary physical chemistry. I Sem., II Sem.
C317 Equilibria and Electrochemistry (2 cr.) P or C: C341 or S341, and MATH M211 or M215. Treatment of analytical data; chemical equilibrium; aqueous and non-aqueous acid-base titrimetry; complex-formation titrations; gravimetric analysis; redox titrations, electrochemical theory; potentiometry; voltammetry; coulometry. II Sem.
C318 Spectrochemistry and Separations (2 cr.) P or C: C341 or S341, and MATH M211 or M215. Ultraviolet, visible, infrared, and luminescence spectrophotometry; flame and electrical discharge techniques; X-ray and mass spectrometric methods; phase equilibria and extractions; counter current distribution; gas, thin-layer liquid, and high-performance liquid chromatography. II Sem.
R340 Survey of Organic Chemistry (3 cr.) P: C118 or permission of the instructor. Classes, structure and reactivity of organic compounds with an emphasis on those found in biological systems. Introduction to spectroscopic methods. Credit given for only one of the following: R340, C341 or S341.
C341 Organic Chemistry I Lectures (3 cr.) N & M P: C106 or C118. Chemistry of carbon compounds. Nomenclature; qualitative theory of valence; structure and reactions. Syntheses and reactions of major classes of monofunctional compounds. Credit not given for both C341 and S341. I Sem., II Sem., SS.
S341 Organic Chemistry I Lectures, Honors (3 cr.) N & M P: S118 or S106, or consent of instructor. For students with unusually good aptitude or preparation. Chemistry of carbon compounds. Nomenclature; qualitative theory of valence; structure and reactions. Syntheses and reactions of major classes of monofunctional compounds. Credit not given for both C341 and S341. I Sem.
C342 Organic Chemistry II Lectures (3 cr.) N & M P: C341. Syntheses and reactions of polyfunctional compounds, natural and industrial products; physical and chemical methods of identification. Credit not given for both C342 and S342. I Sem., II Sem., SS.
S342 Organic Chemistry II Lectures, Honors (3 cr.) N & M P: S341 or consent of instructor. Special course for students with unusually good aptitude or preparation, covering same subject matter as C342. Credit not given for both S342 and C342. II Sem.
C343 Organic Chemistry I Laboratory (2 cr.) P: C341. R: C342 concurrently. Laboratory instruction in the fundamental techniques of organic chemistry and the use of general synthetic methods. Credit not given for both C343 and S343. I Sem., II Sem., SS.
S343 Organic Chemistry I Laboratory, Honors (2 cr.) P: S341. R: S342 concurrently. Special course for students with unusually good aptitude or preparation, covering same subject matter as C343. Credit not given for both S343 and C343. II Sem.
C344 Organic Chemistry II Laboratory (2 cr.) P: C342 and C343. Preparation, isolation, and identification of organic compounds; emphasis on modern research methods. Credit not given for both C344 and S344. I Sem., II Sem., SS.
S344 Organic Chemistry II Laboratory, Honors (2 cr.) P: S342, S343. Special course for students with unusually good aptitude or preparation, covering same subject matter as C344. Credit not given for both S344 and C344. I Sem.
C360 Introductory Physical Chemistry (3 cr.) N & M P: C106 or C118, MATH M119, PHYS P201; or equivalents. Elements of thermodynamics, reaction kinetics, molecular quantum states and spectroscopy. For students not intending to specialize in physical sciences. Credit given only for C360, C361/C362, or S361/S362.
C361 Physical Chemistry of Bulk Matter (3 cr.) N & M P: C106 or C118, MATH M212 or M216, and PHYS P202 or P222. Thermodynamics laws, free energy and chemical potentials, gases and dilute solutions, phase transitions, colligative properties, chemical equilibria, ionic solutions, chemical kinetics and transport processes, current topics. Credit given for only one of the following: C361, S361, or C360. I Sem., II Sem.
S361 Physical Chemistry of Bulk Matter, Honors (3 cr.) N & M P: S106 or S118 or consent of instructor, and MATH M212 or M216. P or C: P 222. Thermodynamics laws, free energy and chemical potentials, gases and dilute solutions, phase transitions, colligative properties, chemical equilibria, ionic solutions, chemical kinetics and transport processes, current topics. For students with unusually good aptitude or preparation. Credit given for only one of the following: C360, C361, or S361. I Sem.
C362 Physical Chemistry of Molecules (3 cr.) P: C118 or C106, MATH M212 or M216, and PHYS P202 or P222. Quantum states and spectroscopy of molecules, statistical thermodynamics, and elementary kinetic theory, current topics. Credit given for only one of the following: C362, S362, or C360. II Sem.
S362 Physical Chemistry of Molecules, Honors (3 cr.) P: S106 or S118, or consent of instructor, and Math M212 or M216. P or C: PHYS P222. Quantum states and spectroscopy of molecules, statistical thermodynamics, and elementary kinetic theory, current topics. For students with unusually good aptitude or preparation. Credit given for only one of the following: C360, C362, or S362. II Sem.
C364 Introduction to Basic Measurements (3 cr.) P: C361 or S361. Graduated laboratory practice relating elementary principles of measurement technologies to current research applications. I Sem., II Sem.
C371 Chemical Informatics I (1 cr.) P: C105 or C117, C106 or C118, I101, I200. Basic concepts of information representation, storage, and retrieval as they pertain to chemistry. Structures, nomenclature, molecular formulas, coding techniques for visualization of chemical structures and properties. Weekly topics presented by faculty from IUB and IUPUI and others via the Internet.
C372 Chemical Informatics II: Molecular Modeling (1 cr.) P: C341. Molecular modeling and computational chemistry; application of quantum mechanics and molecular mechanics to derive structural and energetic information about molecules; conformational analysis; quantitative structure activity relationships (OSAR) and related methods for drug design. II Sem.
Y398 Professional Practice in Chemistry (1-6 cr.) P: Approval of The Department of Chemistry. Designed to provide opportunities for students to receive credit for career-related, full-time work. Evaluation by employer and director of undergraduate studies. Course credit may count as elective hours in the B.S. in chemistry and B.S. in biochemistry degree requirements. May be repeated for a maximum of 6 credit hours.
G407 Chemistry Senior Seminar (1 cr.) P: G207 or instructor permission; senior standing; Chemistry or Biochemistry major. Students will present seminars based on current literature or their C409 research project; assignments will include surveying assigned journals. Focuses will include coverage of recent important developments, further experience in making scientific presentation, and encouragement of good literature reading habits. Not repeatable for credit.
C409 Chemical Research (1-5 cr.; 10 cr. max.) For outstanding students. To be elected only after consultation with the research director and the undergraduate advisor. Cannot be substituted for any course required in a chemistry major. A research thesis is required.
C430 Inorganic Chemistry (3 cr.) N & M P: C106 or C118, or S106 or S118. R: C341 or S341. Structure and bonding of inorganic compounds; survey of chemistry of non-metal and metal elements, coordination compounds, organometallic compounds, mechanisms and reactions. II Sem.
C432 Spectroscopic Methods in Inorganic Chemistry (3 cr.) P: C360 or C361. Chemical applications of group theory and the elucidation of structure and bonding in inorganic molecules and complexes by vibrational, nuclear magnetic resonance, Mossbauer and electronic absorption spectroscopy.
C437 Inorganic Chemistry Laboratory (2 cr.) P: C430 on the Bloomington campus. Synthesis, characterization, and study of chemical and physical properties of inorganic and organometallic compounds.
C443 Organic Spectroscopy (3 cr.) P: C342 and C362. Elucidation of molecular structures by use of IR, UV, NMR, mass spectroscopy, and other methods. I Sem.
C445 Advanced Organic Chemistry Laboratory (1-3 cr.) P or C: C443 or consent of instructor. Experimental problems in organic analysis and synthesis. May be repeated up to a maximum of 3 credits. I Sem.
C460 Nuclear Chemistry (3 cr.) N & M P or C: C360, C361, S361, or graduate standing. Fundamentals of nuclear behavior; nuclear properties, radioactive decay, and nuclear reactions; applications of nuclear phenomena, biological effects of radiation, nuclear analytical techniques, tracers, radioisotope dating, nuclear power, and the origin of the chemical elements. II Sem.
C471 Chemical Information Sources and Services (1 cr.) P or C: C341, S341, or consent of instructor. Techniques for the storage and retrieval of chemical information in both printed and computer-readable formats; sources of chemical information, including chemical abstracts; development of search strategies; online searching of chemical databases. I Sem. Credit given for only one of C400 or C471.
C472 Computer Sources for Chemical Information (1 cr.) P: C400 or C471. Techniques for the utilization of the major computer-based information tools found in academic and industrial environments. II Sem. Credit given for only one of C401 or C472.
C481 Physical Biochemistry (3 cr.) P: C361 and C484. Physical chemistry of biological macromolecules; structure and conformation of proteins and nucleic acids; thermodynamics and kinetics of biochemical reactions. II Sem.
C483 Biological Chemistry (3 cr.) N & M P: 18 credit hours of chemistry, including C342, or consent of instructor. Introduction to structure, chemical properties, and interrelationships of biological substances. I Sem., SS.
C484 Biomolecules and Catabolism (3 cr.) N & M P: 18 credit hours of chemistry, including C341 and C342. Structure and function of cellular components and the generation of phosphate-bond energy. Credit not given for both C484 and C483. I Sem.
C485 Biosynthesis and Physiology (3 cr.) N & M P: C484. Biosynthetic pathways, expression of genetic information, molecular physiology. Credit not given for both C485 and C483. II Sem.
C487 Biochemistry Laboratory (3 cr.) P: C344 or S344 and C484. Laboratory instruction in the fundamental techniques of biochemistry, including assay methods; separation of macromolecules by electrophoresis and chromatography; isolation, purification, and analysis of enzymes; recombinant DNA procedures; polymerase chain reaction (PCR).
C498 Special Topics in Chemistry (1-3 cr.) P: Consent of instructor; section authorization required. Topics in chemistry and biochemistry vary with each offering of this course.
G499 Internship in Chemical Instruction (3 cr.) P: Consent of department. Supervised experience in teaching an undergraduate chemistry course. May not count credit hours toward hours in the major.

Related Research Courses
The following courses may be counted in the Department of Chemistry as equivalent to C409 Chemical Research only by application to the department (Undergraduate Office, CH 021) prior to the start of the research experience. A research thesis must be submitted to the Department of Chemistry at the end of the research experience to complete the equivalency requirement. Note: B.A. students may not use any research course in fulfillment of the chemistry major hours; B.S. students may not count MSCI M450 in the minimum 25 COAS hours required in the major subject area out of the total of 45 chemistry hours required for the major.

• BIOL L490 Individual Study
• MSCI M450 Undergraduate Research in Biomedical Sciences