Recommendations
Mathematics M211 or M215 is strongly recommended, and M212 or M216 is highly desirable for students planning to work in many other fields.

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Major in Biochemistry—B.A.

Purpose
This major is designed for students planning to attend medical or dental school, but who cannot meet all requirements for the B.S. in biochemistry and who do not plan to pursue graduate work or to seek employment in industry. Students must complete the following course work with a grade of C- or better in each course:

1. C105-C125, C106-C126, C341, C342, C343, C484, C485, and C487.
2. A minimum of 3 credit hours selected from the following: C317, C318, C344, C360, C430, C460.
3. Biology L112.
4. Mathematics M119 or M211 or M215.
5. Physics P201 or P221.

Recommendations
Mathematics M211 or M215 is strongly recommended, and M212 or M216 is highly desirable for students planning to work in other fields.

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Special B.A. for Three-Year Predental Students

Purpose
This program is designed for students admitted to the Indiana University School of Dentistry. Students who have completed requirements for this major, the fundamental skills and distribution courses required for the standard B.A. in chemistry or biochemistry, and at least 90 credit hours in courses offered by the College of Arts and Sciences may apply 32 credit hours of their first-year professional courses as elective credit. Students who have been accepted to dental school other than at Indiana University must have special permission from the dean of the College of Arts and Sciences to apply for this degree.

Requirements
Students must complete all of the fundamental skills and distribution requirements that are required for the standard B.A. in chemistry or biochemistry.

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Major in Chemistry—B.S.

Purpose
The B.S. in chemistry is designed to prepare students for graduate work and for jobs in industry as well as for medical and dental schools.

Requirements
Students must complete the following fundamental skills and distribution requirements:

1. Writing, same as B.A. degree.
2. Foreign language, 3 credit hours of any foreign language at the second-year level.
3. Arts and humanities, two courses.
4. Social and historical studies, two courses.
5. Biology, one course.
6. Natural and mathematical sciences, fulfilled by major.

1. 45 credit hours of chemistry, including C315, C317, C318, C341, C342, C343, C344, C361, C362, C364, C430, C471, and either C483 or C484. C103 (except the 2 credit hours which may be counted for C125) and C240 may not be counted in the 45 credit hours required for the major.
2. Mathematics M211 or M215, M212 or M216, and M303, M311, or M343.
3. Physics P221-P222.

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Major in Biochemistry—B.S.

Purpose
The B.S. in biochemistry is designed for students planning to attend medical or dental school, to do graduate work in biochemistry, or to seek employment in industry.

Requirements
Students must complete all of the following fundamental skills and distribution requirements:

1. Writing, same as B.A. degree.
2. Foreign language, 3 credit hours of any foreign language at the second-year level.
3. Arts and humanities, two courses.
4. Social and historical studies, three courses.
5. Natural and mathematical sciences, fulfilled by major.

1. 45 credit hours of chemistry, including C315, C317, C318, C341, C342, C343, C344, C361-C362 or C361-C481, C364 or C487, C471, C484, C485. C103 (except the 2 credit hours which may be counted for C125) and C240 may not be counted in the 45 credit hours required for the major.
2. Mathematics M211 or M215 and M212 or M216.
3. Physics P221-P222.
4. Biology L112 and at least one of the following: L311, L312, M250-M255, M350, M430.

Recommendations
Chemistry C487 is recommended over Chemistry C364. Chemistry C481 is recommended over Chemistry C362.

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American Chemical Society Certified Degree

The American Chemical Society (ACS) Committee on Professional Training has approved Indiana University to offer a Certified Degree in Chemistry. Students who wish to earn the ACS certified degree must complete the requirements for the B.S. in chemistry along with C437, or complete the B.S. in biochemistry along with C430 and C437. Earning the certified degree allows students to be eligible for admission as full members of the ACS following graduation.

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Chemistry Minor

Requirements
15 credit hours or more in chemistry.

1. Required Core Courses: Chem C105, C106, C125, and C341.
2. Electives: Select 2 courses from the following list of lecture courses (4-6 credit hours): C317, C318, C342, C360, C361, C362, C430, C432, C443, C460, C481, C483, C484, C485.
3. 10 credit hours must be taken on the Bloomington campus.
4. A minor GPA of 2.0 is required with no course grade lower than C-.

Departmental Honors Program

The program is designed for especially well-qualified students who wish to acquire an unusually strong foundation in chemistry. Most students completing the honors program enter graduate or professional school. Special courses for outstanding students are offered in general chemistry, S105-S125, S106-S126; and in organic chemistry, S341, S342, S343, and S344. Participants are expected to complete the requirements for a B.S. in chemistry or a B.S. in biochemistry or the following courses: C315, C317, C318, C361, C362, C364, and two 3 credit hour, 400-level courses other than C409 and C445.

The heart of the honors program is participation in an undergraduate research project within a faculty research group. This research generally begins in the freshman or sophomore year and culminates with an honors research thesis at the end of the senior year. Students in the program must maintain a minimum grade point average of 3.3.

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Course Descriptions

C100 The World as Chemistry (3 cr.) N & M For non-science majors, the chemistry of everyday life: fuels, plastics, drugs, water, air, and living systems. Lectures illustrated by demonstrations, films, and molecular models. Readings include articles from current newspapers and magazines. Prerequisite: Curiosity. Credit given for only one of C100, C101, C105, or S105. I Sem., II Sem.
C101 Elementary Chemistry I (3 cr.) N & M Usually taken concurrently with C121. Introduction to chemistry. Lectures and discussion. The two sequences, C101-C121 and C102-C122, usually satisfy programs that require only two semesters of chemistry. Admission to advanced courses on the basis of C101-C121 and C102-C122 is granted only in exceptional cases. May be taken in preparation for C105 by students with deficiencies in chemistry. Credit given for only one of C100, C101, C105, or S105. I Sem., II Sem., SS.
C102 Elementary Chemistry II (3 cr.) N & M P: C101. Usually taken concurrently with C122. Continuation of C101. The chemistry of organic compounds and their reactions followed by an extensive introduction to biochemistry. Lectures and discussion. Credit given for only C102, C106, or S106; however, for students electing to major in allied health sciences after having taken C106 or S106, credit may also be received for C102 with consent of the chemistry undergraduate advisor. I Sem., II Sem., SS.
C103 Introduction to Chemical Principles (5 cr.) N & M P: Scores on placement exams and instructor's permission. To be taken as preparation for C105-C106. Content includes: applications of measurement and chemical formula/equation conversions; modern view of the atom; and solution processes that relate to chemical reactions. Emphasis of lectures and discussion sections will be problem-solving strategies. Laboratory portion of C103 equivalent to C125; a student who takes C103 cannot enroll in C125 for credit.
C105 Principles of Chemistry I (3 cr.) N & M P: Passing grades on the Math Skills Assessment test and the Chemistry Placement Examination; a score of 580 or better on the Mathematics SAT; one year of high school chemistry and C125 concurrently. Basic principles, stoichiometry, thermochemistry, atomic and molecular structure, gases, solution, and topics in descriptive chemistry. Credit given for only one of C100, C101, C105, or S105.
S105 Principles of Chemistry, Honors (3 cr.) N & M P: Placement examination or consent of department, and S125 concurrently. For students with unusual aptitude or preparation. Credit given for only one of C100, C101, C105, or S105. I Sem.
C106 Principles of Chemistry II (3 cr.) N & M P: C105-C125; C126 concurrently. Chemical equilibria with emphasis on acids, bases, solubility, electrochemistry, elementary thermodynamics, chemical kinetics, and selected topics in descriptive chemistry. Credit given for only one of C106, C102, or S106. I Sem., II Sem., SS.
S106 Quantitative Chemistry, Honors (3 cr.) N & M P: S105 and S125, or consent of instructor, and S126 concurrently. For students with unusual aptitude or preparation. Credit given for only one of S106, C102, or C106. II Sem.
C107 Frontiers of Chemical Research (1 cr.) P: One semester of college-level chemistry or consent of instructor. A freshman seminar featuring talks and demonstrations by various faculty about current research in analytical, biological, inorganic, organic, and physical chemistry. II Sem.
C121 Elementary Chemistry Laboratory I (2 cr.) P or C: C101. Introduction to the techniques and reasoning of experimental chemistry. Credit given for only one of the following: C121, C125, or S125. I Sem., II Sem., SS.
C122 Elementary Chemistry Laboratory II (2 cr.) P: C101, C121. P or C: C102. Continuation of C121. Emphasis on organic and biochemical experimental techniques. Credit given for only one of the following: C122, C126, or S126; however, for students electing to major in allied health sciences after having taken C126 or S126, credit may also be received for C122 with consent of the chemistry undergraduate advisor. I Sem., II Sem., SS.
C125 Experimental Chemistry I (2 cr.) C: C105. Introduction to laboratory experimentation, with particular emphasis on the collection and use of experimental data, some properties of solutions, stoichiometry, thermochemistry, and synthesis. Credit given for only one of the following: C125, C103, C121, or S125. I Sem., II Sem., SS.
S125 Experimental Chemistry I, Honors (2 cr.) P: Consent of instructor and S105 concurrently. Laboratory work dealing with properties of gases, liquids, and solids, with atomic and molecular structure, and with chemical equilibrium. Credit given for only one of the following: S125, C121, or C125. I Sem.
C126 Experimental Chemistry II (2 cr.) P: C125. C: C106. A continuation of C125, with emphasis on: equilibria; qualitative analysis; acids and bases; and oxidation-reduction, including electrochemistry, chemical kinetics, and synthesis. Credit given for only one of the following: C126, C122, or S126. I Sem., II Sem., SS.
S126 Experimental Chemistry II, Honors (2 cr.) P: S105 and S125, or consent of instructor. C: S106. Laboratory work dealing with acid-base reactions, with oxidation-reduction reactions, and with the synthesis, characterization, and reactions of inorganic and organic compounds. Credit given for only one of the following: S126, C122, or C126. II Sem.
C203 Macroscopic and Microscopic Chemical Systems (4 cr.) Introduction to the architecture of molecules, atoms and bonds, VSEPR and the structure of inorganic molecules, thermodynamics, chemical reactivity, polymers. Selected topics: materials, membranes, environmental science, modern drug design, nuclear chemistry.
C223 Investigations of Macroscopic and Microscopic Chemical Systems (2 cr.) Laboratory course to accompany C203.
C240 Preparation for Organic Chemistry (1.5 cr.) P: C106 or permission. To develop a standard and comprehensive preparation for the study of organic chemistry. Review of electronic structure, periodicity, bonding, Lewis structures, pKa's, simple nomenclature and molecular geometry; Problem-based approach to developing skills necessary for success in organic chemistry. Course will not count toward chemistry minor or majors.
C315 Chemical Measurements Laboratory I (3 cr.) P: C317, C318. Experimental work in related areas of chemical analysis, instrumentation, and elementary physical chemistry. I Sem., II Sem.
C317 Equilibria and Electrochemistry (2 cr.) P or C: C341 or S341, and MATH M211 or M215. Treatment of analytical data; chemical equilibrium; aqueous and non-aqueous acid-base titrimetry; complex-formation titrations; gravimetric analysis; redox titrations, electrochemical theory; potentiometry; voltammetry; coulometry. II Sem.
C318 Spectrochemistry and Separations (2 cr.) P or C: C341 or S341, and MATH M211 or M215. Ultraviolet, visible, infrared, and luminescence spectrophotometry; flame and electrical discharge techniques; x-ray and mass spectrometric methods; phase equilibria and extractions; counter current distribution; gas, thin-layer liquid, and high-performance liquid chromatography. II Sem.
C335 Inorganic Chemistry Laboratory (1-3 cr.) Preparation of inorganic and organometallic compounds illustrating special and advanced techniques, including characterization by modern physical methods. May be repeated up to a maximum of 3 credits. II Sem.
C341 Organic Chemistry I Lectures (3 cr.) N & M P: C106. Chemistry of carbon compounds. Nomenclature; qualitative theory of valence; structure and reactions. Syntheses and reactions of major classes of monofunctional compounds. Credit not given for both C341 and S341. I Sem., II Sem., SS.
S341 Organic Chemistry I Lectures, Honors (3 cr.) N & M P: S106 or consent of instructor. For students with unusually good aptitude or preparation. Credit not given for both S341 and C341. I Sem.
C342 Organic Chemistry II Lectures (3 cr.) N & M P: C341. Syntheses and reactions of polyfunctional compounds, natural and industrial products; physical and chemical methods of identification. Credit not given for both C342 and S342. I Sem., II Sem., SS.
S342 Organic Chemistry II Lectures, Honors (3 cr.) N & M P: S341 or consent of instructor. Special course for students with unusually good aptitude or preparation, covering same subject matter as C342. Credit not given for both S342 and C342. II Sem.
C343 Organic Chemistry I Laboratory (2 cr.) P: C341. R: C342 concurrently. Laboratory instruction in the fundamental techniques of organic chemistry and the use of general synthetic methods. Credit not given for both C343 and S343. I Sem., II Sem., SS.
S343 Organic Chemistry I Laboratory, Honors (2 cr.) P: S341. R: S342 concurrently. Special course for students with unusually good aptitude or preparation, covering same subject matter as C343. Credit not given for both S343 and C343. II Sem.
C344 Organic Chemistry II Laboratory (2 cr.) P: C342 and C343. Preparation, isolation, and identification of organic compounds; emphasis on modern research methods. Credit not given for both C344 and S344. I Sem., II Sem., SS.
S344 Organic Chemistry II Laboratory, Honors (2 cr.) P: S342, S343. Special course for students with unusually good aptitude or preparation, covering same subject matter as C344. Credit not given for both S344 and C344. I Sem.
C360 Introductory Physical Chemistry (3 cr.) N & M P: C106, MATH M119, PHYS P201; or equivalents. Elements of thermodynamics, reaction kinetics, molecular quantum states and spectroscopy. For students not intending to specialize in physical sciences. Lectures and discussion. Credit given only for C360, C36/C362, or S361/S362. I Sem., II Sem., SS.
C361 Physical Chemistry of Bulk Matter (3 cr.) N & M P: C106, MATH M212 or M216, and PHYS P202 (or P or C: PHYS P222). Thermodynamics laws, free energy and chemical potentials, gases and dilute solutions, phase transitions, colligative properties, chemical equilibria, ionic solutions, chemical kinetics and transport processes, current topics. Credit given for only one of the following: C361, S361, or C360. I Sem., II Sem.
S361 Physical Chemistry of Bulk Matter, Honors (3 cr.) P: S106, or consent of instructor, and MATH M212 or M216. P or C: PHYS P222. Thermodynamics laws, free energy and chemical potentials, gases and dilute solutions, phase transitions, colligative properties, chemical equilibria, ionic solutions, chemical kinetics and transport processes, current topics. For students with unusually good aptitude or preparation. Credit given for only one of the following: C360, C361, or S361. I Sem.
C362 Physical Chemistry of Molecules (3 cr.) P: C106, MATH M212 or M216, and PHYS P202 (or P or C: PHYS P222). Quantum states and spectroscopy of molecules, statistical thermodynamics, and elementary kinetic theory, current topics. Credit given for only one of the following: C362, S362, or C360. II Sem.
S362 Physical Chemistry of Molecules, Honors (3 cr.) P: S106, or consent of instructor, and MATH M212 or M216. P or C: PHYS P222. Quantum states and spectroscopy of molecules, statistical thermodynamics, and elementary kinetic theory, current topics. For students with unusually good aptitude or preparation. Credit given for only one of the following: C360, C362, or S362. II Sem.
C364 Introduction to Basic Measurements (3 cr.) P: C361 or S361. Graduated laboratory practice relating elementary principles of measurement technologies to current research applications. I Sem., II Sem.
C371 Chemical Informatics I (1 cr.) P: C105, C106, I101, I200. Basic concepts of information representation, storage, and retrieval as they pertain to chemistry. Structures, nomenclature, molecular formulas, coding techniques for visualization of chemical structures and properties. Weekly topics presented by faculty from IUB and IUPUI and others via the Internet.
C372 Chemical Informatics II (1 cr.) P: C371, C341. Basic concepts of information representation, storage, and retrieval as they pertain to chemistry with emphasis on organic and biochemical knowledge. Spectral data representation and retrieval, crystallographic data systems, pattern recognition, instrumentation and laboratory networking, combinatorial chemistry, molecular modeling, and bioinformatics.
Y398 Professional Practice in Chemistry (1-6 cr.) P: Approval of the Department of Chemistry. Designed to provide opportunities for students to receive credit for career-related, full-time work. Evaluation by employer and director of undergraduate studies. Course credit may count as elective hours in the B.S. in chemistry and B.S. in biochemistry degree requirements. May be repeated for a maximum of 6 credit hours.
C409 Chemical Research (1-5 cr.; 10 cr. max.) For outstanding students. To be elected only after consultation with the research director and the undergraduate advisor. Cannot be substituted for any course required in a chemistry major. A research thesis is required.
C430 Inorganic Chemistry (3 cr.) N & M P: C106 or S106. R: C341 or S341. Structure and bonding of inorganic compounds; survey of chemistry of non-metal and metal elements, coordination compounds, organometallic compounds, mechanisms and reactions. II Sem.
C432 Spectroscopic Methods in Inorganic Chemistry ( 3 cr.) P: C360 or C361. Chemical applications of group theory and the elucidation of structure and bonding in inorganic molecules and complexes by vibrational, nuclear magnetic resonance, Mossbauer and electronic absorption spectroscopy.
C437 Inorganic Chemistry Laboratory (2 cr.) P: C430 on the Bloomington campus. Synthesis, characterization, and study of chemical and physical properties of inorganic and organometallic compounds.
C443 Organic Spectroscopy (3 cr.) P: C342 and C362. Elucidation of molecular structures by use of IR, UV, NMR, mass spectroscopy, and other methods. I Sem.
C445 Advanced Organic Chemistry Laboratory (1-3 cr.) P or C: C443 or consent of instructor. Experimental problems in organic analysis and synthesis. May be repeated up to a maximum of 3 credits. I Sem.
C460 Nuclear Chemistry (3 cr.) N & M P or C: C360, C361, S361, or graduate standing. Fundamentals of nuclear behavior; nuclear properties, radioactive decay, and nuclear reactions; applications of nuclear phenomena, biological effects of radiation, nuclear analytical techniques, tracers, radioisotope dating, nuclear power, and the origin of the chemical elements. II Sem.
C471 Chemical Information Sources and Services (1 cr.) P or C: C341, S341, or consent of instructor. Techniques for the storage and retrieval of chemical information in both printed and computer-readable formats; sources of chemical information, including chemical abstracts; development of search strategies; online searching of chemical databases. I Sem. Credit given for only one of C400 or C471.
C472 Computer Sources for Chemical Information (1 cr.) P: C400 or C471. Techniques for the utilization of the major computer-based information tools found in academic and industrial environments. II Sem. Credit given for only one of C401 or C472.
C481 Physical Biochemistry (3 cr.) P: C361 and C484. Physical chemistry of biological macromolecules; structure and conformation of proteins and nucleic acids; thermodynamics and kinetics of biochemical reactions. II Sem.
C483 Biological Chemistry (3 cr.) N & M P: 18 credit hours of chemistry, including C342, or consent of instructor. Introduction to structure, chemical properties, and interrelationships of biological substances. I Sem., SS.
C484 Biomolecules and Catabolism (3 cr.) N & M P: 18 credit hours of chemistry, including C341 and C342. Structure and function of cellular components and the generation of phosphate-bond energy. Credit not given for both C484 and C483. I Sem.
C485 Biosynthesis and Physiology (3 cr.) N & M P: C484. Biosynthetic pathways, expression of genetic information, molecular physiology. Credit not given for both C485 and C483. II Sem.
C487 Biochemistry Laboratory (3 cr.) P: C344 or S344 and C484. Laboratory instruction in the fundamental techniques of biochemistry, including assay methods; separation of macromolecules by electrophoresis and chromatography; isolation, purification, and analysis of enzymes; recombinant DNA procedures; polymerase chain reaction (PCR).
C498 Special Topics in Chemistry (1-3 cr.) P: Consent of instructor; section authorization required. Topics in chemistry and biochemistry vary with each offering of this course.

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Related Research Courses

The following courses may be counted in the Department of Chemistry as equivalent to C409 Chemical Research only by application to the department (Instructional Support Office, CH 021) prior to the start of the research experience. A research thesis must be submitted to the Department of Chemistry at the end of the research experience to complete the equivalency requirement.

Note: B.A. students may not use any research course in fulfillment of the chemistry major hours; B.S. students may not count MSCI M450 in the minimum 25 College of Arts and Sciences hours required in the major subject area out of the total of 45 chemistry hours required for the major.

• BIOL L490 Individual Study
• MSCI M450 Undergraduate Research in Biomedical Sciences