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2007-2009 School of Medicine Indianapolis Campus Bulletin: Table of Contents


Courses od School of Medicine

School of Medicine
Academic Bulletin

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Department of Microbiology and Immunology

Chair: Professor Broxmeyer

The courses listed below are primarily intended for students seeking the M.S. or Ph.D. degree in microbiology and immunology, and for medical students seeking a combined M.D. and graduate degree. Complete program information is provided in the Graduate School Bulletin and/or departmental brochures.

J510 Infectious Microbes and Host Interactions (3cr.) P: graduate-level biochemistry. Emphasis on the molecular and cellular events that permit pathogenic bacteria and viruses to enter human cells and disrupt cell function while evading the host’s immune system. Staff

J601 Medical Immunology (2 cr.) Introduction to natural and acquired immune mechanisms, with consideration of their significance to medicine. Topics will include both normal and abnormal immune processes, including recovery from and prevention of disease, immune-mediated pathological processes, tumor immunology, immunodeficiency and auto-immunity. Designed to precede and complement J822 General and Medical Microbiology. Wilde

J800 Advanced Microbiology (cr. arr.) P: consent of instructor. The approach to problems in microbiology, including the application of techniques of bacteriology, genetics, immunology, mycology, parasitology, virology, and zoology. Staff

J802 Introduction to Research (2 cr.) P: consent of instructor. Laboratory research instruction in microbiology and immunology. Purpose is to introduce students to three different research programs in microbiology and/or immunology. Staff

J805 Molecular Immunology (3 cr.) P: B500 or equivalent; consent of instructor. Characterization of immunologically relevant molecules in terms of molecular genetics, synthesis and assembly, structure-function and evolutionary relationships, and functional roles in immune responses. Entities to be considered include members of the immunoglobulin superfamily and functionally associated molecules. Dent

J807 Current Topics in Immunology (2 cr.) P: graduate standing, J805 or J840 or equivalent, or consent of instructor. Discussion and review of current literature in selected topics in immunology. Emphasis on molecular and cellular events in lymphocyte activation and regulation. Topic varies from year to year. May be repeated for credit. Staff

J810 Research in Microbiology (cr. arr.) P: consent of instructor. Data obtained from work in this course may be used to meet thesis requirements for advanced degrees in medicine, dentistry, or in the Graduate School. Staff

J821 Microbial Pathogenicity (3 cr.) This course will consider in detail determinants of microbial virulence and mechanisms of host responses to infection and how these factors interact in the pathogenesis of infectious diseases. Staff

J822 General and Medical Microbiology (3 cr.) Lectures covering the biology of various pathogenic organisms such as bacteria, viruses, fungi, and parasites, their role in human disease with emphasis on determinants of microbial virulence, the mechanisms of host responses to infection, and the role of these factors in the pathogenesis of disease. Schloemer

J826 Bacteriology (3 cr.) P: J601 or J822 or equivalent and consent of instructor. General concepts of bacteriology. Staff

J828 Virology (3 cr.) P: B106 or B500 or equivalent; consent of instructor. Basic biological principles of viruses; viruses that cause disease in man and lower animals; interactions of animal viruses with host cells; and bacteriophage systems. He and Alkhatib

J829 Current Topics in Molecular Genetics of Microorganisms (2 cr.) P: graduate standing, J821, J828 or G865, consent of instructor. In-depth study of a specific topic in contemporary molecular genetics of microorganisms. Topic varies; may be taken for credit more than once. Staff

J830 Seminar in Microbiology (1 cr.) P: consent of instructor. Current literature in all fields in microbiology. Staff

J840 Mechanisms of Immune Regulation (2 cr.) P: consent of instructor. A current overview of the cellular mechanisms that regulate immune responses. Topics include cells and cytokines in antigen presentation, lymphocyte activation and function, development, and tolerance. Blum/Klemsz

J842 Neoplastic Determinants (2 cr.) P: G865, G817 or equivalent and consent of instructor. Focus on the genetic basis of the cancer phenotype. Consider effects of DNA sequence mutations, chromosomal rearrangements, and/or introduction of new genetic information on DNA repair, oncogene products, and tumor suppressors. Intra- and intercellular consequences of these direct alterations will be studied. Roman

J854 Hematopoiesis (2 cr.) P: G817, G865, and consent of instructor. Principles of blood cell formation, including the regulation of production, biologic function, and cell culture and recombinant DNA technologies that contribute to our understanding. Stem cells, growth factors, cytokine involvement, gene transfer/gene therapy and clinical applications. Broxmeyer/Haak

J899 Senior Elective in Microbiology and Immunology (hrs. and cr. arr.) A variety of electives is offered within the department. Specific information on each elective is available in the Senior Elective Program Course Listing, which is updated and published in February of each year. These electives are offered in the Medical Center facilities and in approved programs in clinics and hospitals throughout the state. Staff

G837 Mammalian DNA Repair and Disease (3 cr.) P: consent of instructor. The molecular biology of genetic repair and mutation; emphasis on human systems and human disease states related to DNA repair; mechanisms of DNA repair and regulation of DNA repair in mammalian cells. Smith/Lee

G865 Fundamental Molecular Biology (1-5 cr.) P: B800 or equivalent. Principles of molecular structure function and biosynthesis; core information regarding prokaryotic and eukaryotic gene continuity and metabolic coordination; introduction to multicellular systems and problems. (Joint program with Biochemistry.) Edenberg

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