School of Medicine
(An asterisk [*] denotes associate membership in University Graduate School faculty.)
Clinical Associate Professors
Clinical Assistant Professors
Joe C. Christian Professor of Medical and Molecular Genetics
(See also general University Graduate School requirements.)
The graduate courses listed below are not all offered in any given academic year. Inquiries on the availability and suitability of any particular course should be directed to the graduate advisor. In addition to those areas indicated by specific course offerings, extensive opportunities for interdepartmental research are also available.
Q580 Basic Human Genetics (3 cr.) P: general genetics and consent of the instructor. An introduction to the genetics of human traits and heritable diseases. Emphasis will be on general aspects of eukaryote genetics as it applies to humans, but some prokaryote genetics will be included for comparison.
Q606 Foundations in Genetic Counseling (3 cr.) Introduction to the principles and practice of genetic counseling. Topics include genetic counseling techniques, prenatal diagnosis counseling, pediatric/adult counseling, and support services.
Q610 Clinical Genetics Practicum (3 cr.) P: consent of the instructor. Methods for obtaining medical and family histories, approaches to evaluation of individuals and families with genetic disorders, and techniques for providing genetic counseling. May be repeated once for credit.
Q611 Genetics Analysis Laboratory (1-2 cr.) P: consent of the instructor. Computer storage and retrieval of family data. Use of programs for genetic analysis. Includes analysis of twins, families of twins, and genetic linkage and segregation.
Q612 Molecular and Biochemical Genetics (3 cr.) Molecular and biochemical aspects of gene function in various genetic disorders. Emphasis on the DNA lesion when known, on aberrations in the metabolic pathways, and on structural defects. Discussion of hemoglobinopathies, phenylketonuria, storage diseases, and other conditions.
Q613 Molecular and Biochemical Genetics Laboratory (2 cr.) The student will learn to perform many of the molecular and biochemical techniques for the determination of genetic markers that can be used for diagnosis, genotyping, and forensic applications.
Q614 Psychological Aspects of Genetic Counseling (3 cr.) PP: one course in introductory or abnormal psychology. Introduction to theory and research in the field of genetic counseling. Topics include risk assessment, attitude assessment, and decision-making. The social, ethical, and legal aspects of the delivery of genetic services are also covered.
Q615 Prenatal Diagnosis Practicum (3 cr.) Training in prenatal genetic counseling. Counseling referrals may include advanced maternal age, abnormal prenatal screening, abnormal ultrasound, or other pregnancy complications.
Q616 Specialty Clinics Practicum (2 cr.) P: consent of the instructor. An overview of the long-term management of patients living with a variety of genetic conditions. Students may provide genetic counseling while in these clinics.
Q617 Genetic Counseling Practicum (1-2 cr.) P: Q606, Q610, consent of instructor. Practice advanced genetic counseling skills in a weekly clinic. Develop proficiency in pedigree construction, patient education, and psychosocial assessment/counseling.
Q620 Human Cytogenetics (3 cr.) P: consent of the instructor, basic genetics. Study of chromosome structure and replication, X-inactivation, meiosis, numerical and structural rearrangements in humans, and cytogenetics of malignancies.
Q621 Human Cytogenetics Laboratory (3 cr.) P: basic genetics, Q620, and consent of instructor. Current techniques in human cytogenetics. May be taken concurrently with Q620.
Q622 Cytogenetics of Malignancies (2-3 cr.) PP: consent of instructor. This course will examine the biologic implications of cytogenetic abnormalities found in malignancies. Aberrant gene function as a result of cytogenetic abnormalities will be stressed.
Q630 Population Genetics (3 cr.) PP: basic genetics. Basic probability and Bayes theorem, as applied to genetic counseling. Effects of mutation and selection on the survival of alleles in a population; consequences of consanguinity and inbreeding; methods of analysis including segregation and linkage including nonparametric methods; quantitative genetics such as twin studies, and heritability.
Q631 Quantitative Genetics (2 cr.) P: G651 and G652 or equivalent. Inheritance of human quantitative traits, partitioning of phenotypic variation, estimation of genetic variance and heritability, methods of analyzing resemblance among relatives including nuclear families, twins, and half-siblings (currently inactive).
Q640 Special Topics in Human Genetics (1-3 cr.; 9 cr. max.) A continuing nonrepeating series of lectures on newer advances in human genetics; discussions in specific areas of human genetics not currently available to all students. Additional credits may be obtained by study of a specific area under individual tutelage.
Q642 Dermatoglyphics (2 cr.) PP: consent of instructor. Formation, development, classification and variation of finger, palm, and footprint patterns (dermatoglyphics) in humans; interpretation of results of quantitative and statistical techniques utilized in the study of the inheritance of dermatoglyphic traits, variation in twins, and applications in clinical genetics.
Q660 Medical Genetics Seminar (2 cr.) P: basic genetics. Topics chosen from aspects of medical genetics not extensively treated elsewhere. Various phases of research in medicine from a genetic and clinical point of view. Students may receive credit during each semester of residence on the Medical Center campus.
Q730 Methods in Human Genetics (3 cr.) P: basic genetics, differential calculus, and Q630 or equivalent. Sampling methods employed in study of human genetics; methods for analysis of segregation, linkage, mutation, and selection with family data collected under various forms of ascertainment.
Q800 Medical Genetics Research (cr. arr.)**
**This course is eligible for a deferred grade.
G504 Introduction to Research Ethics (2 cr.) Introduction to the basic concepts of research ethics. The course will cover historical development of concern with ethics in science as well as practical information needed by students working in the science today. Format will be lecture and discussion.
G651-G652 Introduction to Biostatistics I-II (3-3 cr.) Data description, sampling variation and distributions, interval estimation, and tests of hypotheses involving binomial, normal, t, F, and X2 distribution; one-way analysis of variance, bivariate regression and correlation, higher order experimental designs, and associated analysis of variance; use of statistical analysis programs on computer.
G901 Advanced Research (6 cr.) For Ph.D. students who have at least 90 credit hours. May be taken for maximum of six semesters (not available in summer semesters).